Getting back into a SD , 2005 , any advice ...

I'm going to go look at a 2005 F250 , 5.4 , manual , work truck pkg with A/C. 83300 miles

In other words , a plain janer.

Any known issues to look for on these gasser motors and whatever else?
Manual hubs .. any thing to be aware of?
axles front & rear ...
manual tranny ...
etc.

I had a 2001 F250 7.3L , but got rid of it awhile back , so I have a fairly decent idea what to look for with these trucks , but this is 4 years newer and a manual , 5.4L ...
So any advice , let me know.
Thanks ,
Eric